A new UCLA Health study has discovered in mouse models that #genes associated with repairing mismatched #DNA are critical in eliciting damages to #neurons that are most vulnerable in #Huntington's disease and triggering downstream #pathologies and motor impairment, shedding light on disease mechanisms
#Medical #Neuroscience #Genetics #Psychiatry #BehavioralScience #sflorg
https://www.sflorg.com/2025/02/med02112501.html

One protein of polyglutamine folds into a particular shape to start forming the #amyloid that causes #Huntington’s and other #neurodegenerative diseases. #Neuroscience https://elifesciences.org/digests/86939/stick-twist-or-fold?utm_source=mastodon&utm_medium=social&utm_campaign=organic

People with #Huntington’s disease lose control of their bodies and minds. The symptoms are caused by #protein clumps in the #nervecells. Supported by a Marie Skłodowska-Curie Individual Fellowship, Andrea Quezada aims to create atomic models of these fibrils.
https://www.mdc-berlin.de/news/news/mapping-structure-huntingtons-brain-clumps

Was ist #Huntington - Podcast https://music.amazon.de/podcasts/05d34f25-2fe8-4c9b-8584-26455ff94aab/episodes/4dfe44bd-8208-4171-85eb-75fd618931c5/neurodegeneration-kompakt-huntington-kompakt-was-ist-huntington-mit-pd-dr-patrick-weydt #HuntingtonAwarenessMonth #LetsTalkAboutHD /mn

Wir freuen uns schon morgen am #TagderseltenenErkrankungen, dazu gehören u. a. #Ataxie oder #ALS, aber eben auch #Huntington, zu einem Instragram-Live-Talk einzuladen. Ab 16 Uhr starten wir drüben https://www.instagram.com/dzne_de /db

Forscher haben einen Wirkstoff identifiziert, der bei #Huntington-Patienten den Spiegel des krankheitsverursachenden Huntingtin reduziert. Bisher war unklar, welcher Mechanismus dahintersteckt.
http://redirect.doccheck.com/c2d8j4

Challenge #160: What triggers the incurable #HuntingtonsDisease?

Scientists at the #mdcBerlin use the #FruitFly to investigate how #Huntington's disease develops in the #brain and how it could be stopped.

More: https://www.helmholtz.de/en/research/helmholtz-challenges/challenge/what-triggers-the-incurable-huntingtons-disease/ #InspiredByChallenges @helmholtz

Guten Morgen - Tässle Kaffee? ️

Habe in „Rückzug oder Kreuzzug?“ die leider weit verbreitete #Huntington-These vom „Kampf der Kulturen“ widerlegt gefunden. Verweise stattdessen auf den Riss zwischen demokratischem #Monismus und feind-seligem #Dualismus quer DURCH die Religionen (wie #Christentum) und Weltanschauungen (wie #Liberalismus). DLF-Radiointerview mit Beispiel #Trump: https://www.deutschlandfunkkultur.de/rueckzug-oder-kreuzzug-100.html