The K+ channel KCNK1 is differentially expressed in many #tumors, but why? Study shows that KCNK1 overexpression in #BreastCancer promotes proliferation, invasion & #metastasis by increasing #glycolysis & activating #LactateDehydrogenase. #PLOSBiology https://plos.io/3VTNdCr
Puzzle solved 
: A #CharitéBerlin team has found out how cells deal with extra chromosomes.
The previously unknown mechanism could help identify lines of attack in dealing with treatment-resistant #tumors & fungal #infections. The fundamental findings have now been published in #Nature.
Our spin-off "Captain T Cell" raised €8.5 million in seed funding. Focused on developing T cells to target solid #tumors, Captain T Cell intends to use the funds to move a new generation of #Tcell therapies closer toward clinical application.
The #startup builds on years of research and innovations. It utilizes technologies developed at the #mdcBerlin, which provided financial and infrastructural support throughout the pre-seed phase and remains a close partner.
https://www.mdc-berlin.de/news/news/captain-t-cell-secures-seed-financing-round
Researchers discovered that #tumors use a messenger substance to influence #immunecells in an early phase of the immune response. This could significantly improve #cancer immunotherapies: http://go.tum.de/368607
A.Eckert
Migrating #immune cells like neutrophils can cause damage, when they infiltrate #tumors. To enable a better analysis of these migrating cells, researchers from @MedEssen @unidue @isas_Leibniz have developed the #ComplexEye #microscope. #drugs #imaging
https://nachrichten.idw-online.de/2023/12/11/new-microscope-complexeye-and-ai-enable-faster-migration-analysis-of-immune-cells
Bei der Bildung eines #Tumors verändert das Gewebe seine Konsistenz, z.B. von weich zu hart. Welche mechanischen Prozesse dahinterstecken, untersucht nun eine neue Forschungsgruppe an der #CharitéBerlin.
Dazu nutzt sie eine neu entwickelte Methode, die ein #MRT mit akustischen Wellen verbindet und so die Steifigkeit von Gewebe berechnen kann. Die @dfg_public fördert das Vorhaben mit ~5 Mio. Euro.
Exciting #research from ECRC scientist @anton_gh on #DNA rings floating freely in cell nuclei of many, particularly aggressive #tumors! Discover their potential role in cancer (therapies) in his @NatureGenet paper: https://www.mdc-berlin.de/news/press/how-cancer-genes-become-independent #CancerResearch #mdcBerlin @ChariteBerlin
